Margaux Lecacheur

This study shows that ECM stiffness influences dedifferentiated melanoma cells via DDR1/2 and YAP, affecting their behavior and drug resistance.

This study shows that NAD+ supplementation restores circadian rhythms and reverses cardiac aging in mice by reprogramming the diurnal transcriptome.

This study identifies USP9X as a mechanosensitive deubiquitinase that stabilizes YAP to enhance tumor cell invasiveness and drug resistance.