Author

Kirsty McCann

Burnet InstituteORCID 0000-0002-2427-241XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:plant (other)· 2 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alyssa E. BarryiD· 2 shared Brad E. SleebsiD· 2 shared Madeline G. DansiD· 2 shared Paul R. GilsoniD· 2 shared William NguyeniD· 2 shared Zahra RazookiD· 2 shared Alan F. CowmaniD· 1 shared Anna NgoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCell Biology

Alyssa E. BarryORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 24, 2025

Deconvolution of the on-target activity of plasmepsin V peptidomimetics in P. falciparum parasites

Wenyin Su, William Nguyen, Ghizal Siddiqui…·Madeline G. Dans

This study investigates the on-target activity of plasmepsin V peptidomimetics in Plasmodium falciparum by combining chemoproteomic methods and genetic validation.

DOI 10.1101/2025.07.24.666510

plant (other)experimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintMar 18, 2025

Aryl N-acetamide compounds exert antimalarial activity by acting as agonists of rhomboid protease PfROM8 and cation channel PfCSC1.

Coralie Boulet, Joyanta K. Modak, Natalie A. Counihan…·Paul R. Gilson

This study identifies M-512 as an agonist of PfROM8 and PfCSC1, which are essential for Plasmodium falciparum growth, and shows that their dysregulation reduces parasite viability.

3 citations

plant (other)experimental assay

𝕏 PostBluesky