Author

Wenyin Su

The University of MelbourneORCID 0000-0002-6400-644XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:plant (other)· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alan F. CowmaniD· 2 shared Anna NgoiD· 2 shared Anthony T. PapenfussiD· 2 shared Brad E. SleebsiD· 2 shared Danushka S. MarapanaiD· 2 shared Jerzy Michal DziekaniD· 2 shared Jocelyn Sietsma PeningtoniD· 2 shared Madeline G. DansiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersMicrobiology

Alan F. CowmanORCID

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2 papers

Recent·Most cited

Dual plasmepsin IX and X inhibitors are refractory to development of resistance

Paola Favuzza, Madeline G. Dans, Wenyin Su, Jennifer K. Thompson, Anthony N. Hodder, Anna Ngo, Jocelyn Sietsma Penington, Danushka S. Marapana, Jerzy Michal Dziekan, Anthony T. Papenfuss, Manuel de Lera Ruiz, Rachael Coyle, Marcus C. S. Lee, John A. McCauley, Kym N. Lowes, , Alan F. Cowman

This study evaluates resistance development to PMX-selective and dual PMIX/X inhibitors in Plasmodium falciparum, finding that dual inhibitors have a higher resistance barrier.

PLoS Pathogens · Sep 8, 2026Peer-reviewedMicrobiology

Deconvolution of the on-target activity of plasmepsin V peptidomimetics in P. falciparum parasites

Wenyin Su, William Nguyen, Ghizal Siddiqui, Jerzy Michal Dziekan, Danushka S. Marapana, Jocelyn Sietsma Penington, Somya Mehra, Zahra Razook, Kirsty McCann, Anna Ngo, Kate E. Jarman, Alyssa E. Barry, Anthony T. Papenfuss, Paul R. Gilson, Darren J. Creek, , Madeline G. Dans

This study investigates the on-target activity of plasmepsin V peptidomimetics in Plasmodium falciparum by combining chemoproteomic methods and genetic validation.

bioRxiv · Jul 24, 2025 · PreprintCell Biology