Norihiro Kato

The paper develops a model to assess genetic and epigenetic contributions to plasma lipid levels and finds that combining rare variants, PRS, and MRS improves LDL-C prediction.

The paper develops a statistical method to infer ploidy from single-cell ATAC-seq data and applies it to human and mouse cell atlases to systematically detect polyploidy across cell types.

The paper shows that early treatment with RAS inhibitors in SHR reduces kidney renin expression and lowers blood pressure long-term through genetic and epigenetic changes.

This study uses single-nucleus ATAC-seq and machine learning to identify gene regulation modules and core genes in NAFLD progression in rats.

This paper identifies 56 new type 2 diabetes loci in 433,540 East Asian individuals through a meta-analysis of GWAS data.