Sambamurthy Chandrasekaran

This study identifies two copper transporters in Toxoplasma gondii and shows their roles in parasite metabolism and persistence.

The paper compares neuronal transcriptional responses to Toxoplasma gondii and RNA viruses, identifying conserved and pathogen-specific immune responses in neurons.

This study shows immune pressure targets Toxoplasma gondii bradyzoites, which mitigate tissue damage and promote host-parasite survival.

This paper introduces dual perturb-seq, a method combining CRISPR screening and single-cell RNA-sequencing to identify host-microbe transcriptional interactions, revealing new effector proteins in Toxoplasma gondii.

This study shows that IFN-γ stimulated murine and human neurons can clear Toxoplasma gondii parasites, challenging the dogma that neurons cannot mount anti-parasitic defenses.