Author

Emily F. Merritt

University of ArizonaORCID 0000-0002-9449-4683Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Anita A. KoshyiD· 2 shared Adam BuntzmaniD· 1 shared Alexander N. JamboriD· 1 shared Andrew S. KennedyiD· 1 shared Ashwin SomasundaramiD· 1 shared Austin C. ConkliniD· 1 shared Ayesha Swannigan· 1 shared Brandon M. PrattiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

Anita A. KoshyORCID

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Author profile →

3 papers

Recent·Most cited

Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential

Brandon M. Pratt, Genevieve Nicole Mullins, Nolan James Brown, William D. Green, Jennifer L. Modliszewski, Fucong Xie, Lara van Rooyen, Vasyl Zhabotynsky, Alexander N. Jambor, Gabrielle Heather Cannon, Jarred Michael Green, Andrew S. Kennedy, Coral del Mar Alicea Pauneto, Huitong Shi, Emily F. Merritt, , J. Justin Milner

The paper uses in vivo single-cell gain-of-function screening to identify latent transcriptional programs that reprogram T cells into synthetic states with enhanced therapeutic potential.

bioRxiv · Jan 8, 2026 · PreprintImmunology

IFN-γ stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii

Sambamurthy Chandrasekaran, Joshua A. Kochanowsky, Emily F. Merritt, Joseph S. Lagas, Ayesha Swannigan, Anita A. Koshy

This study shows that IFN-γ stimulated murine and human neurons can clear Toxoplasma gondii parasites, challenging the dogma that neurons cannot mount anti-parasitic defenses.

Nature Communications · Aug 8, 2022Peer-reviewedMicrobiology

Transcriptional profiling reveals T cells cluster around neurons injected with Toxoplasma gondii proteins

Emily F. Merritt, Hannah J. Johnson, Zhee Sheen Wong, Adam Buntzman, Austin C. Conklin, Carla M. Cabral, Casey E. Romanoski, Jon P. Boyle, Anita A. Koshy

The paper uses RNA-seq to compare transcriptional profiles of neurons infected with Toxoplasma gondii, bystander neurons, and controls, finding immune cell transcripts enriched in infected neurons.

mSphere · Sep 1, 2020Peer-reviewedBioinformatics