Author

Amelia Edwards

The Francis Crick Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Andreas SagneriD· 1 shared Anita A. KoshyiD· 1 shared Anna K. Marciniak-CzochraiD· 1 shared Eloise J. LockyeriD· 1 shared Francesca TorelliiD· 1 shared François GuillemotiD· 1 shared James BriscoeiD· 1 shared Julien Delile· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperDevelopmental Biology

Andreas SagnerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mapping host-microbe transcriptional interactions by dual perturb-seq

Simon W Butterworth, Kristina Kordova, Sambamurthy Chandrasekaran, Kaitlin K. Thomas, Francesca Torelli, Eloise J. Lockyer, Amelia Edwards, Robert J. Goldstone, Anita A. Koshy, Moritz Treeck

This paper introduces dual perturb-seq, a method combining CRISPR screening and single-cell RNA-sequencing to identify host-microbe transcriptional interactions, revealing new effector proteins in Toxoplasma gondii.

bioRxiv · Apr 21, 2023 · PreprintMolecular Biology

Progressive changes in hippocampal stem cell properties ensure lifelong neurogenesis

Lachlan Harris, Piero Rigo, Thomas Stiehl, Zachary B. Gaber, Sophie H. L. Austin, Maria del Mar Masdeu, Amelia Edwards, Noelia Urbán, Anna K. Marciniak-Czochra, François Guillemot

The paper shows that hippocampal stem cells in mice undergo progressive behavioral changes that reduce depletion and ensure lifelong neurogenesis.

Cell stem cell · Feb 15, 2021Peer-reviewedDevelopmental Biology

Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

Julien Delile, Teresa Rayón, Manuela Melchionda, Amelia Edwards, James Briscoe, Andreas Sagner

scRNA-seq of 21465 mouse neural tube cells (e9.5-e13.5) maps spinal progenitor and neuron types, validates new subtype markers, and reveals temporally staged transcription-factor modules.

Development · Mar 7, 2019Peer-reviewedDevelopmental Biology✦ In-depth digest