Author

Janay P. Franklin

University of North Carolina at Chapel HillORCID 0000-0002-2444-8403Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:rat· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Anze TesteniD· 3 shared Emily A. WittiD· 3 shared Kathryn J. ReissneriD· 3 shared Tania J. BellingeriD· 3 shared Eden V. HarderiD· 2 shared Jonathan W. VanRyziniD· 2 shared Ronald KimiD· 2 shared Austin J. HepperlaiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersNeuroscience

Anze TestenORCID

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4 papers

Recent·Most cited

Abstinence from cocaine self-administration promotes microglia pruning of astrocytes which drives cocaine-seeking behavior

Anze Testen, Jonathan W. VanRyzin, Tania J. Bellinger, Ronald Kim, Han Wang, Matthew J. Gastinger, Emily A. Witt, Janay P. Franklin, Haley A. Vecchiarelli, Katherine Picard, Marie‐Ève Tremblay, Kathryn J. Reissner

bioRxiv · Sep 20, 2024 · PreprintNeuroscience

Investigating cocaine- and abstinence-induced effects on astrocyte gene expression in the nucleus accumbens

Janay P. Franklin, Anze Testen, Piotr A. Mieczkowski, Austin J. Hepperla, Gogce C. Crynen, Jeremy M. Simon, Jonathan Wood, Eden V. Harder, Tania J. Bellinger, Emily A. Witt, N. LaShae Powell, Jonathan W. VanRyzin, Kathryn J. Reissner

This study identifies molecular changes in astrocytes of the nucleus accumbens in rats following cocaine self-administration and abstinence using RiboTag and RNA-seq.

bioRxiv · Aug 5, 2024 · PreprintNeuroscience

Abstinence-dependent effects of long-access cocaine self-administration on nucleus accumbens astrocytes are observed in male, but not female rats

Ronald Kim, Anze Testen, Eden V. Harder, Natalie E. Brown, Emily A. Witt, Tania J. Bellinger, Janay P. Franklin, Kathryn J. Reissner

The paper examines the effects of long-access cocaine self-administration and abstinence on nucleus accumbens astrocytes in male and female rats, finding significant reductions in male rats but not females.

eNeuro · Aug 22, 2022Peer-reviewedNeuroscience

The synthetically produced predator odor 2,5-dihydro-2,4,5-trimethylthiazoline increases alcohol self-administration and alters basolateral amygdala response to alcohol in rats.

Viren H. Makhijani, Janay P. Franklin, Kalynn J. Van Voorhies, Brayden Fortino, Joyce Besheer

This study shows that repeated exposure to the predator odor TMT increases alcohol self-administration and alters amygdala response to alcohol in rats, suggesting a link between PTSD-like stress and AUD.

Psychopharmacology · Sep 25, 2020Peer-reviewedNeuroscience