Kalynn J. Van Voorhies

This study evaluates the effects of SBI-553, a β-arrestin-biased allosteric modulator of NTSR1, on ethanol-related behaviors in rodents, finding reduced ethanol consumption and altered sensitivity to ethanol effects.

This study shows that predator odor stress increases male rats' sensitivity to alcohol via GABAA receptor changes in the prelimbic cortex, but not in females.

This study shows that predator odor exposure increases sensitivity to alcohol's interoceptive effects and boosts GABAergic gene expression in brain regions linked to stress and addiction.

This study shows that TLR3 agonism increases alcohol consumption in rats, with females being more sensitive to lower doses than males.

This study shows that TLR7 activation with imiquimod increases ethanol self-administration and induces TLR-related gene expression in rats, with sex-specific effects on drinking behavior and molecular responses.

This study investigates how mGlu2 and mGlu3 NAMs affect alcohol's interoceptive effects in rats, finding they reduce these effects in both sexes with potential sex differences in response.

The paper tests a CB1 receptor NAM, RTICBM-74, showing it reduces alcohol intake in rats without affecting locomotion or sucrose self-administration.

This study investigates the role of the nucleus reuniens in modulating context reactivity to predator odor stressor TMT in rats, showing context-dependent effects of RE inactivation on behavioral responses.

This study shows that central amygdala mineralocorticoid receptors influence alcohol self-administration in rats, with MR antagonists reducing alcohol consumption.

This study shows that repeated exposure to the predator odor TMT increases alcohol self-administration and alters amygdala response to alcohol in rats, suggesting a link between PTSD-like stress and AUD.