Haley A. Vecchiarelli

This study examines how different cannabis THC:CBD compositions affect oligodendrocyte progenitor cells in mice after acute vapor inhalation, finding morphological and mitochondrial changes similar to early differentiation.

This study examines the effects of prenatal THC exposure on mouse brain development using MRI across the lifespan, finding sex-dependent neurodevelopmental impacts.

This study compares 2D and 3D image analysis of microglial morphology in mouse brains, finding similar and novel results, consistent conclusions, and the importance of nested statistical designs.

The paper quantifies astrogliosis in a Syrian hamster model of mild-moderate COVID-19, finding a transient, female-specific increase in GFAP signal density in the cortex at 3 days post-inoculation.

This study identifies dark microglia in postnatal mouse hippocampus, showing they perform synapse remodeling via phagocytosis and trogocytosis and depend on TREM2.

This study shows that JZL184 improves motor learning and striatal plasticity in YAC128 HD mice by increasing 2-AG levels, suggesting endocannabinoid modulation as a potential therapeutic target for HD.

This study shows that the FAAH C385A polymorphism exacerbates hormone-mediated feeding in mice under specific environmental conditions, affecting metabolic outcomes.

This study shows that postsynaptic pannexin-1 regulates glutamate release and network excitability by facilitating anandamide clearance and modulating TRPV1 activity.