Author

Anze Testen

Medical University of South CarolinaORCID 0000-0002-4779-8705Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Emily A. WittiD· 3 shared Janay P. FrankliniD· 3 shared Kathryn J. ReissneriD· 3 shared Tania J. BellingeriD· 3 shared Eden V. HarderiD· 2 shared Jonathan W. VanRyziniD· 2 shared Ronald KimiD· 2 shared Austin J. HepperlaiD· 1 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersNeuroscience

Emily A. WittORCID

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4 papers

Recent·Most cited

Abstinence from cocaine self-administration promotes microglia pruning of astrocytes which drives cocaine-seeking behavior

Anze Testen, Jonathan W. VanRyzin, Tania J. Bellinger, Ronald Kim, Han Wang, Matthew J. Gastinger, Emily A. Witt, Janay P. Franklin, Haley A. Vecchiarelli, Katherine Picard, Marie‐Ève Tremblay, Kathryn J. Reissner

bioRxiv · Sep 20, 2024 · PreprintNeuroscience

Formation of an Enduring Ensemble of Accumbens Neurons Leads to Prepotent Seeking for Cocaine Over Natural Reward Cues

Reda Chalhoub, Anze Testen, Jordan Hopkins, Camille L. Carthy, Peter W. Kalivas

The paper shows that cocaine-trained mice have stable D1-MSNs in the NAcore that predict cue-induced cocaine seeking, unlike sucrose.

bioRxiv · Aug 5, 2024 · PreprintNeuroscience

Investigating cocaine- and abstinence-induced effects on astrocyte gene expression in the nucleus accumbens

Janay P. Franklin, Anze Testen, Piotr A. Mieczkowski, Austin J. Hepperla, Gogce C. Crynen, Jeremy M. Simon, Jonathan Wood, Eden V. Harder, Tania J. Bellinger, Emily A. Witt, N. LaShae Powell, Jonathan W. VanRyzin, Kathryn J. Reissner

This study identifies molecular changes in astrocytes of the nucleus accumbens in rats following cocaine self-administration and abstinence using RiboTag and RNA-seq.

bioRxiv · Aug 5, 2024 · PreprintNeuroscience

Abstinence-dependent effects of long-access cocaine self-administration on nucleus accumbens astrocytes are observed in male, but not female rats

Ronald Kim, Anze Testen, Eden V. Harder, Natalie E. Brown, Emily A. Witt, Tania J. Bellinger, Janay P. Franklin, Kathryn J. Reissner

The paper examines the effects of long-access cocaine self-administration and abstinence on nucleus accumbens astrocytes in male and female rats, finding significant reductions in male rats but not females.

eNeuro · Aug 22, 2022Peer-reviewedNeuroscience