Pre-Omicron Immunity Generates IgG⁺ but Not IgA⁺ Memory B Cells Reactive to Omicron Spike Protein
Theocharis Tsoleridis, I Singh, David Onion…·Jonathan K. Ball
This study shows that pre-Omicron immunity generates IgG+ but not IgA+ memory B cells reactive to Omicron spike protein, indicating broad antigenic recognition but weakened mucosal antibody defense.