Author

Benjamin Van Loy

Rega Institute for Medical ResearchORCID 0000-0002-2491-7222Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Annelies StevaertiD· 2 shared Bert VanmecheleniD· 2 shared Julie VandeputiD· 2 shared Lieve M. J. NaesensiD· 2 shared Nikolai BakirtzoglouiD· 2 shared Piet MaesiD· 2 shared Ria Van Berwaer· 2 shared Abhimanyu Kumar SinghiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersMicrobiology

Annelies StevaertORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 29, 2026

Mechanistic insights into coronavirus inhibition by a distinct base-modified adenosine analog targeting the viral polymerase

Nikolai Bakirtzoglou, Barbara Selisko, Yucen Huang…·Annelies Stevaert

This paper investigates the mechanism of 6-ethyl-modified 7-deazaadenosine (EDA) as a coronavirus inhibitor, showing it stalls viral polymerase without causing mutagenesis.

DOI 10.64898/2026.10.28.761875

experimental assay

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MicrobiologyPLoS PathogensPeer-reviewedFeb 11, 2025

A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses

Benjamin Van Loy, Eugènia Pujol, Kenichi Kamata…·Annelies Stevaert

This paper identifies EPB-113, a guanidine-based inhibitor of coronavirus nsp15 endoribonuclease, which suppresses viral replication and selects for interferon-susceptible mutants.

9 citationstop 3%

humanexperimental assay

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