Author
Rega Institute for Medical ResearchORCID 0000-0003-3554-1088Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Nikolai Bakirtzoglou, Barbara Selisko, Yucen Huang…·Annelies Stevaert
This paper investigates the mechanism of 6-ethyl-modified 7-deazaadenosine (EDA) as a coronavirus inhibitor, showing it stalls viral polymerase without causing mutagenesis.
Jan Lawrenz, Lukas Wettstein, Armando Rodríguez…·Jan Münch
This paper identifies Trypstatin, a Kunitz-type protease inhibitor that inhibits TMPRSS2 and related proteases, showing broad-spectrum antiviral activity against SARS-CoV-2, influenza, and other respiratory viruses.
Benjamin Van Loy, Eugènia Pujol, Kenichi Kamata…·Annelies Stevaert
This paper identifies EPB-113, a guanidine-based inhibitor of coronavirus nsp15 endoribonuclease, which suppresses viral replication and selects for interferon-susceptible mutants.