Bogdan A. Stoica

Interaction of high-fat diet and brain trauma alters adipose tissue macrophages and brain microglia associated with exacerbated cognitive dysfunction.

This study examines how high-fat diet and brain trauma interact to alter macrophages in adipose tissue and microglia in the brain, leading to worsened cognitive function.

Brain injury accelerates the onset of a reversible age-related microglial phenotype associated with hyperphagocytosis and inflammatory neurodegeneration

This study shows that brain injury accelerates age-related microglial changes linked to hyperphagocytosis and neurodegeneration in old mice.

Microglial depletion with CSF1R inhibitor during chronic phase of experimental traumatic brain injury reduces neurodegeneration and neurological deficits

This study shows that removing microglia with a CSF1R inhibitor after TBI reduces neurodegeneration and improves neurological outcomes.