Author

Yun Li

University of Maryland, BaltimoreORCID 0000-0003-2040-4451Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yun Li10 papers · University of North Carolina at Chapel Hill

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:electronic health records· 1

Frequent Co-Authors

Junfang WuiD· 3 shared Hangnoh LeeiD· 2 shared Hui LiiD· 2 shared Shaolin LiuiD· 2 shared Zhuofan LeiiD· 2 shared Alan I. FadeniD· 1 shared Balaji KrishnamacharyiD· 1 shared Bogdan A. StoicaiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersNeuroscience

Junfang WuORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 6, 2026

Sex-dependent chronic neurological dysfunction following isoflurane anesthesia and surgery is associated with circulating extracellular vesicle-mediated neuroinflammatory signaling

Yun Li, Ruth Park, Balaji Krishnamachary…·Junfang Wu

This study shows that isoflurane anesthesia and surgery cause chronic sex-dependent neurological issues in mice, linked to changes in brain transcriptomes and circulating extracellular vesicles.

DOI 10.64898/2026.07.31.742052

mousebulk RNA-seq

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NeurosciencebioRxivPreprintAug 5, 2026

Isoflurane and surgery aggravate APOE4-dependent lipid dysregulation and neural dysfunction, leading to neurological impairment in male mice

Yun Li, Yuanyuan Ji, Çoşar Uzun…·Junfang Wu

This study shows that isoflurane anesthesia and surgery worsen lipid dysregulation and neural dysfunction in APOE4 mice, leading to neurological impairments.

DOI 10.64898/2026.07.31.742028

mousebulk RNA-seq

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NeuroscienceScience AdvancesPeer-reviewedMar 8, 2023

Brain injury accelerates the onset of a reversible age-related microglial phenotype associated with hyperphagocytosis and inflammatory neurodegeneration

Rodney M. Ritzel, Yun Li, Yun Jiao…·Junfang Wu

This study shows that brain injury accelerates age-related microglial changes linked to hyperphagocytosis and neurodegeneration in old mice.

91 citationstop 1%

mouseexperimental assay

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