Author

Indranil Sinha

Stockholm UniversityORCID 0000-0002-2513-5927Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Amanda Ramilo Amor· 2 shared Anna NilssoniD· 2 shared Frida HolmiD· 2 shared Ola HermansoniD· 2 shared Qingfei Jiang· 2 shared Sabina Enlund· 2 shared Shahrzad Shirazi FardiD· 2 shared Akshit Jain· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

Amanda Ramilo Amor

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3 papers

Recent·Most cited

Molecular BiologyCell ReportsPeer-reviewedAug 22, 2026

RNA degradation by DIS3 is a necessary step in the resolution of backtracked transcription complexes

Elin Enervald, Shruti Jain, Marcel Tarbier…·Neus Visa

This paper shows that DIS3's 3-5 exoribonuclease activity degrades backtracked RNA, resolving stalled RNAPII complexes and enabling transcription elongation.

DOI 10.1016/j.celrep.2026.117886

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintAug 29, 2025

METTL13 Promotes Pre-Leukemic Transformation and the Development of Pediatric Leukemia

Sabina Enlund, Chae-Eun Lim, Isabella Hoang…·Frida Holm

This study identifies METTL13 as an oncogenic factor promoting pre-leukemic transformation and T-ALL development through its regulation by ADAR1.

DOI 10.1101/2025.08.29.673071

humanexperimental assay

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Cancer BiologyExperimental HematologyPeer-reviewedJan 9, 2025

A Distinct Alternative mRNA Splicing Profile Identifies the Oncogenic CD44 Transcript Variant 3 in KMT2A-Rearranged Pediatric T-cell Acute Lymphoblastic Leukemia Cells

Amanda Ramilo Amor, Sabina Enlund, Indranil Sinha…·Frida Holm

The paper identifies a distinct mRNA splicing profile in KMT2A-rearranged pediatric T-ALL, highlighting CD44v3 as a potential biomarker and therapeutic target.

DOI 10.1016/j.exphem.2025.104712

humanbulk RNA-seq

𝕏 PostBluesky