Neus Visa

This paper shows that DIS3's 3-5 exoribonuclease activity degrades backtracked RNA, resolving stalled RNAPII complexes and enabling transcription elongation.

This paper identifies IGS38, a lncRNA that enhances rRNA transcription by altering chromatin structure and promoting RNA polymerase I promoter escape.

This study shows ADAR1 regulates alternative splicing through both RNA editing-dependent and editing-independent mechanisms, with the latter having greater impact.

The paper shows the exosome degrades chromatin-associated RNAs and helps maintain chromatin homeostasis by regulating repetitive sequences and centromere organization.

The paper shows that ADAR2-mediated RNA editing of DNA:RNA hybrids is essential for DNA double strand break repair by facilitating DNA end resection.

This study shows BRG1 affects alternative splicing by altering RNA binding factor interactions with RNA, with some effects independent of its ATPase activity.