Natalia Martín-Martín

This study shows that loss of PGC1α in prostate cancer leads to ECM remodeling via CTHRC1, promoting tumor aggressiveness.

This study analyzes PTEN-deficient prostate tumors to reveal stromal reprogramming and senescent paracrine communication through transcriptional network analysis and single-cell RNA-Seq.

This study characterizes the transcriptome of metastatic hormone-naive prostate cancer, identifying stroma remodelling and SOX11's role in metastasis.

This study shows that loss of UFMylation promotes prostate cancer metastasis by reprogramming glucose metabolism towards hexosamine biosynthesis.

This study identifies spermidine synthase as a PGC1-regulated secreted protein that mediates paracrine tumor suppression in prostate cancer, highlighting a non-cell autonomous mechanism.

The paper identifies TCF19 as an androgen-responsive gene upregulated in metastatic prostate cancer, showing its role in vessel homeostasis and metastatic progression.