Author

Parthasaradhireddy Tanguturi

University of ArizonaORCID 0000-0002-2566-9312Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

John M. StreicheriD· 2 shared Barnali Paul· 1 shared Brian K. KobilkaiD· 1 shared Brian S. J. BlaggiD· 1 shared Christopher M. BrackettiD· 1 shared Christopher S. Campbell· 1 shared Chunlai CheniD· 1 shared David I. DuroniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

John M. StreicherORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintFeb 21, 2026

Discovery and dynamic pharmacology of μ-opioid receptor positive allosteric modulators

Evan S. O’Brien, Junzheng Wang, Parthasaradhireddy Tanguturi…·Brian K. Kobilka

This study discovers μ-opioid receptor positive allosteric modulators (PAMs) and investigates their dynamic mechanism of action to enhance opioid agonist activity while reducing side effects.

1 citation

humanproteomics

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NeuroscienceScientific ReportsPeer-reviewedJun 26, 2024

Inhibiting Spinal Cord-Specific Hsp90 Isoforms Reveals a Novel Strategy to Improve the Therapeutic Index of Opioid Treatment

David I. Duron, Parthasaradhireddy Tanguturi, Christopher S. Campbell…·John M. Streicher

This paper shows that inhibiting specific spinal cord Hsp90 isoforms enhances opioid pain relief while reducing tolerance and side effects.

14 citations

mouseexperimental assay

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