Author

Claes Fryklund

Lund UniversityORCID 0000-0002-2581-8832Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Maria SwanbergiD· 2 shared Alexandra Hellberg· 1 shared Christian SimonssoniD· 1 shared Filip Fredlund· 1 shared Hannah A. StaleyiD· 1 shared Joaquín PardoiD· 1 shared Josefin MalmbergiD· 1 shared Karin G. StenkulaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPhysiology

Maria SwanbergORCID

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2 papers

Recent·Most cited

PhysiologyDisease Models & MechanismsPeer-reviewedAug 6, 2026

Fixed-dose streptozotocin combined with high-fat diet induces a stable type 2 diabetes-like phenotype in C57BL/6J mice

Claes Fryklund, Christian Simonsson, Alexandra Hellberg…·Maria Swanberg

This study shows that fixed-dose streptozotocin in HFD-fed mice induces a stable T2D-like phenotype, contrasting with weight-adjusted dosing which causes variability.

DOI 10.1242/dmm.053071

mousemetabolomics

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NeuroscienceNeurobiology of DiseasePeer-reviewedFeb 13, 2025

Lack of neuroprotection after systemic administration of the soluble TNF inhibitor XPro1595 in an rAAV6-α-Syn+PFFs-induced rat model for Parkinson's disease

Filip Fredlund, Claes Fryklund, Olivia Trujeque-Ramos…·Maria Swanberg

This study shows that systemic XPro1595, a TNF inhibitor, does not protect against -Syn-induced Parkinson's-like pathology in rats, despite being effective in other neurodegeneration models.

5 citations

ratexperimental assay

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