Author

Blaise Alexander Clarke

Johns Hopkins UniversityORCID 0000-0002-2585-8391Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

Christopher D. MorrisoniD· 1 shared David H. McDougaliD· 1 shared Diana A Albarado· 1 shared Florina CorpodeaniD· 1 shared Hans‐Rudolf BerthoudiD· 1 shared Heike MünzbergiD· 1 shared Ingie HongiD· 1 shared Julia Brill· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Christopher D. MorrisonORCID

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2 papers

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedApr 28, 2025

Dissociation of SYNGAP1 Enzymatic and Structural Roles: Intrinsic Excitability and Seizure Susceptibility

Julia Brill, Blaise Alexander Clarke, Ingie Hong, Richard L. Huganir

This study shows that SYNGAP1's structural role, not its enzymatic GAP activity, is critical for seizure susceptibility in heterozygous KO mice, while its GAP activity affects intrinsic excitability.

15 citationstop 1%

mouseelectronic health records

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NeuroscienceMolecular MetabolismPeer-reviewedNov 19, 2024

FGF21 acts in the brain to drive macronutrient-specific changes in behavioral motivation and brain reward signaling

Md Shahjalal Hossain Khan, Sora Q. Kim, Robert C. Ross…·Christopher D. Morrison

This study shows that FGF21 in the brain enhances the reward value of protein, increasing motivation to consume it during protein restriction.

26 citations

mouseexperimental assay

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