Molecular BiologybioRxivPreprint
ATP-dependent citrate lyase Drives Left Ventricular Dysfunction by Metabolic Remodeling of the Heart
Shijie Liu, Seth T. Gammon, Lin Tan…·Anja Karlstaedt
This study shows that ACL loss in the heart increases glucose oxidation and reduces citrate efflux, leading to metabolic remodeling and cardiac dysfunction.
3 citations