Author

Sally M. Dewhurst

Rockefeller University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Andrew RowaniD· 1 shared Ariana HuebneriD· 1 shared Charles SwantoniD· 1 shared Emilia L. LimiD· 1 shared Gareth A. WilsoniD· 1 shared Huasong TianiD· 1 shared Joel A. RosieneiD· 1 shared Julie M. BehriD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenomics

Andrew RowanORCID

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2 papers

Recent·Most cited

Structural variant evolution after telomere crisis

Sally M. Dewhurst, Xiaotong Yao, Joel A. Rosiene, Huasong Tian, Julie M. Behr, Nazario Bosco, Kaori Takai, Titia de Lange, Marcin B. Imielinski

The paper investigates structural variants (SVs) generated during telomere crisis, showing that BFB cycles and chromothripsis can occur in clones that escape telomere crisis.

Nature Communications · Apr 7, 2021Peer-reviewedGenomics

Whole Genome Doubling mitigates Muller’s Ratchet in Cancer Evolution

Saioa López, Emilia L. Lim, Ariana Huebner, Michelle Dietzen, Thanos P. Mourikis, Thomas B.K. Watkins, Andrew Rowan, Sally M. Dewhurst, Nicolai J. Birkbak, Gareth A. Wilson, Mariam Jamal‐Hanjani, Charles Swanton, Nicholas McGranahan

The paper investigates how whole genome doubling (WGD) in cancer may mitigate Muller’s Ratchet by reducing negative selection on mutations in essential genes after duplication.

bioRxiv · Jan 7, 2019 · PreprintGenomics