Author
University of UdineORCID 0000-0002-2639-1893Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Alessia Bellina, Matilde Clarissa Malfatti, Tobias Obermann…·Gianluca Tell
This study investigates APE1's role in repairing damaged telomeric i-motif structures and its interaction with PCBP1 in maintaining telomere integrity.
Giovanna Mangiapane, Michela Notarangelo, Giulia Canarutto…·Gianluca Tell
The paper identifies APE1-dependent miRNAs secreted via exosomes, showing their prognostic significance in cancer and their regulation by APE1 and hnRNPA2B1.
Giuseppe Dall’Agnese, Nancy M. Hannett, Kalon J. Overholt…·Gianluca Tell
This study creates an endogenous fluorescent APE1 cell line to show that APE1 accumulates in nucleoli via RNA G-quadruplex structures and lysine residues, linking phase separation to its functional switch between rRNA processing and DNA repair.
Alessia Bellina, Matilde Clarissa Malfatti, Gilmar F. J. Salgado…·Gianluca Tell
This study identifies APE1 as an RNA G-quadruplex binding protein that regulates miR-92b expression by modulating rG4 structure folding and miRNA maturation in cancer cells.
Damiano Tosolini, Giulia Antoniali, Emiliano Dalla, Gianluca Tell
The paper investigates the role of phase partitioning in DNA damage response by analyzing APE1's interactome for signs of liquid-liquid phase separation.