Gilmar F. J. Salgado

Self-Assembled Nucleolipid G-Quadruplexes Act as Multitarget Decoys for Oncogene Suppression in Pancreatic Cancer

This paper introduces NLG4, self-assembled nucleolipid G-quadruplexes that inhibit pancreatic cancer by targeting multiple oncogenes and pathways.

Recognition and Resolution of KRAS 5'UTR RNA G-Quadruplexes by hnRNPA1

This study identifies RNA G-quadruplexes in the 5'UTR of KRAS mRNA and demonstrates their interaction with hnRNPA1, revealing a post-transcriptional regulatory mechanism.

Apurinic/apyrimidinic endodeoxyribonuclease 1 contributes to the repair of damaged intercalated-motif of telomeric sequences

This study investigates APE1's role in repairing damaged telomeric i-motif structures and its interaction with PCBP1 in maintaining telomere integrity.

Membrane partition and structural reorganization induced by anti-psychotics with distinct clinical profiles

This study compares how two antipsychotics, chlorpromazine and clozapine, partition into and modify lipid membranes, revealing differences in their membrane remodeling effects despite differing D2R antagonism strengths.

The Apurinic/Apyrimidinic Endodeoxyribonuclease 1 is an RNA G-quadruplex binding protein and regulates miR-92b expression in cancer cells

This study identifies APE1 as an RNA G-quadruplex binding protein that regulates miR-92b expression by modulating rG4 structure folding and miRNA maturation in cancer cells.