Author

Laura Botana

Instituto de Salud Carlos IIIORCID 0000-0002-2652-9880Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Organism:chicken / avian· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ana-Maria NăstaseiD· 1 shared Clément RegnaultiD· 1 shared Enrique CalvoiD· 1 shared Eugenia CarrilloiD· 1 shared Fernanda Bertuccez CordeiroiD· 1 shared Gema Garcia-Guirado· 1 shared Ismael Santa‐MaríaiD· 1 shared J P Fernández Vázquez· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Ana-Maria NăstaseORCID

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2 papers

Recent·Most cited

Human SHED-derived extracellular cues activate a specialized neuroprotective and regenerative program in developing retinal ganglion cells

Marian Mellén, Gema Garcia-Guirado, Laura Botana, Enrique Calvo, Yariliz Sencion, Mattia Biondo, Javier Díez-Mata, J P Fernández Vázquez, Ismael Santa‐María, Maite Iglesias

This study shows that SHED-derived extracellular factors enhance axonal regeneration and neuronal survival in retinal ganglion cells through distinct paracrine mechanisms.

bioRxiv · Jun 26, 2026 · PreprintCell Biology

Alignment of multiple metabolomics LC-MS datasets from disparate diseases to reveal fever-associated metabolites

Ana-Maria Năstase, Michael Peter Barrett, Washington Bolivar Cardenas, Fernanda Bertuccez Cordeiro, Mildred Zambrano, Joyce Andrade, Juan Chang, Mary Regato, Eugenia Carrillo, Laura Botana, Javier Moreno, Clément Regnault, Kathryn H. Milne, Philip J. Spence, J. Alexandra Rowe, Simon Rogers

This study aligns metabolomics LC-MS datasets from malaria, leishmaniasis, and Zika virus to identify fever-associated metabolites, finding the kynurenine pathway as most affected.

PLoS neglected tropical diseases · Jul 24, 2023Peer-reviewedBioinformatics