Genetics of posttraumatic stress disorder and cardiovascular conditions using Lifes Essential 8, Electronic Health Records, and Heart Imaging
Jie Shen, Wander L. Valentim, Eleni Friligkou, Cassie M. Overstreet, Karmel W. Choi, Dóra Koller, Christopher J. O’Donnell, Murray B. Stein, Joel E. Gelernter, Haitao Lv, Ling Sun, Guido J. Falcone, Renato A Polimanti, Gita A. Pathak
This study identifies shared genetic loci and genes between PTSD and cardiovascular conditions using GWAS across multiple data sources and finds overlapping biological pathways and drug targets.
medRxiv · Aug 20, 2024 · PreprintGenetic & Genomic Medicine