Adriana Migliorini

Extra-lineage tissue programs define the transcription states of human pancreatic cancer

The paper identifies four epithelial transcription states in pancreatic cancer and links their origins to early developmental processes.

Development of an on-chip fluorescence anisotropy immunoassay for human C-peptide secretion reveals a general roadmap for tracer optimization

The paper develops an on-chip fluorescence anisotropy immunoassay for human C-peptide by optimizing antibody-tracer pairs to achieve high sensitivity and fast kinetics for microfluidic measurement.

Delineating mouse β-cell identity during lifetime and in diabetes with a single cell atlas

This paper integrates multiple scRNA-seq datasets to create a mouse islet atlas, revealing new insights into β-cell states and differences across diabetes models.

Macrophages heterogeneity and significance during human fetal pancreatic development

The paper identifies fetal pancreatic macrophage subsets and shows their role in promoting endocrine cell differentiation and tissue engraftment.