Author

Jianxia Guo

University of PittsburghORCID 0000-0002-2732-8220Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Jan Hendrik BeumeriD· 2 shared Anthony ChristodoulouiD· 1 shared Brian F. KieseliD· 1 shared Cecilia W. Y. LoiD· 1 shared Christopher J. BakkenistiD· 1 shared Cody Ruck· 1 shared David A Clump· 1 shared Devin Raine Everaldo CortesiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Jan Hendrik BeumerORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 28, 2026

Transient ATR inhibition following ionizing radiation enhances immune-mediated antitumor response and survival

Joshua J. Deppas, Brian F. Kiesel, Frank P. Vendetti…·Jan Hendrik Beumer

The paper shows that transient ATR inhibition with ceralasertib and elimusertib, but not berzosertib, enhances antitumor immune responses and survival when combined with ionizing radiation in a mouse model.

DOI 10.64898/2026.05.25.727700

mousebulk RNA-seq

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Developmental BiologybioRxivPreprintFeb 13, 2024

Mitigation of Fetal Irradiation Injury from Mid-Gestation Total Body Radiation with Mitochondrial-Targeted GS-Nitroxide JP4-039

Yijen Lin Wu, Anthony Christodoulou, Jan Hendrik Beumer…·Joel S. Greenberger

Maternal administration of mitochondrial-targeted JP4-039 mitigates fetal brain injury and preserves mitochondrial function after mid-gestation radiation exposure.

2 citations

mouseimaging

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