Author

Brian F. Kiesel

University of PittsburghORCID 0000-0002-4214-7524Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher J. BakkenistiD· 1 shared David A Clump· 1 shared Frank P. VendettiiD· 1 shared Jan Hendrik BeumeriD· 1 shared Jianxia GuoiD· 1 shared Joshua J. DeppasiD· 1 shared Kristine L. CooperiD· 1 shared Maria Stefania diMayorca· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Christopher J. BakkenistORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMay 28, 2026

Transient ATR inhibition following ionizing radiation enhances immune-mediated antitumor response and survival

Joshua J. Deppas, Brian F. Kiesel, Frank P. Vendetti…·Jan Hendrik Beumer

The paper shows that transient ATR inhibition with ceralasertib and elimusertib, but not berzosertib, enhances antitumor immune responses and survival when combined with ionizing radiation in a mouse model.

DOI 10.64898/2026.05.25.727700

mousebulk RNA-seq

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