Author

Scott A. Foster

GenentechORCID 0000-0002-2773-7999Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:simulation· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Andrew Goetz· 1 shared Anqi ZhuiD· 1 shared Bartosz CzechiD· 1 shared Benjamin HaleyiD· 1 shared Darlene Dela Cruz· 1 shared Eva LiniD· 1 shared Frances Shanahan· 1 shared Jawahar SudhamsuiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperSystems Biology

Andrew Goetz

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2 papers

Recent·Most cited

Systems BiologyCancersPeer-reviewedAug 22, 2024

Computational modeling of drug response identifies mutant-specific constraints for dosing panRAF and MEK inhibitors in melanoma

Andrew Goetz, Frances Shanahan, Logan Brooks…·Luca Gerosa

This study uses computational modeling and preclinical data to identify optimal dosing strategies for panRAF and MEK inhibitors in melanoma, revealing distinct dose requirements based on NRAS vs BRAF mutations.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologyCell ReportsPeer-reviewedJun 1, 2024

Accelerated drug resistant variant discovery with an enhanced, scalable mutagenic base editor platform

Kristel M. Dorighi, Anqi Zhu, Jean‐Philippe Fortin…·Benjamin Haley

The paper develops a scalable mutagenic base editor platform to identify drug-resistant variants in cancer genomes efficiently.

10 citations

humanwhole-exome sequencing

𝕏 PostBluesky