Grigori Y. Rychkov

This study identifies distinct brainstem circuits activated by splanchnic and pelvic spinal afferent pathways from the mouse colorectum, showing their differential roles in sensory processing and visceromotor responses.

This study identifies two existing drugs that reduce KCNT1 channel activity and seizure activity in Drosophila models, suggesting potential new treatments for KCNT1-epilepsy.

This study models human KCNT1-epilepsy in Drosophila by expressing patient mutations and shows drug responses, demonstrating the utility of Drosophila as a model for assessing treatments.