Author

Zeeshan Shaukat

University of South AustraliaORCID 0000-0002-4507-7752Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Assay:electrophysiology· 1

Frequent Co-Authors

Grigori Y. RychkoviD· 2 shared Jonathan D. LippiatiD· 2 shared Leanne M. DibbensiD· 2 shared Michael G. RicosiD· 2 shared Rashid HussainiD· 2 shared Anowarul IslamiD· 1 shared Bethan A. ColeiD· 1 shared Chiao Xin LimiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPharmacology & Toxicology

Grigori Y. RychkovORCID

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2 papers

Recent·Most cited

Identification of new KCNT1-epilepsy drugs by in silico, cell and Drosophila modelling.

Michael G. Ricos, Bethan A. Cole, Rashid Hussain, Grigori Y. Rychkov, Zeeshan Shaukat, Nadia Pilati, Stephen P. Muench, Katie J. Simmons, Leanne M. Dibbens, Jonathan D. Lippiat

This study identifies two existing drugs that reduce KCNT1 channel activity and seizure activity in Drosophila models, suggesting potential new treatments for KCNT1-epilepsy.

bioRxiv · May 22, 2025 · PreprintPharmacology & Toxicology

Modelling human KCNT1-epilepsy in Drosophila: a seizure phenotype and drug responses

Rashid Hussain, Chiao Xin Lim, Zeeshan Shaukat, Anowarul Islam, Emily A. Caseley, Jonathan D. Lippiat, Grigori Y. Rychkov, Michael G. Ricos, Leanne M. Dibbens

This study models human KCNT1-epilepsy in Drosophila by expressing patient mutations and shows drug responses, demonstrating the utility of Drosophila as a model for assessing treatments.

bioRxiv · Apr 11, 2023 · PreprintNeuroscience