Author

Harshavardhana H. Ediga

University of CincinnatiORCID 0000-0002-2809-5449Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Satish Kumar MadalaiD· 3 shared Anil Goud JeggaiD· 2 shared Andreas SchedliD· 1 shared Chanukya P. VemulapalliiD· 1 shared Christoph EnglertiD· 1 shared Debora I. SinneriD· 1 shared Dimitry Popov· 1 shared Francis X. McCormackiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersPathology

Satish Kumar MadalaORCID

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3 papers

Recent·Most cited

Wilms tumor 1 impairs apoptotic clearance of fibroblasts in distal fibrotic lung lesions

Harshavardhana H. Ediga, Chanukya P. Vemulapalli, Vishwaraj Sontake, Pradeep Kumar Patel, Hikaru Miyazaki, Dimitry Popov, Martin Borch Jensen, Anil Goud Jegga, Steven Kenneth Huang, Christoph Englert, Andreas Schedl, Nishant Gupta, Francis X. McCormack, Satish Kumar Madala

This study shows WT1 promotes fibroblast survival and ECM production in IPF by impairing apoptotic clearance.

Journal of Clinical Investigation · Jun 10, 2025Peer-reviewedPathology

Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea.

Nicholas X. Russell, Kaulini Burra, Ronak Shah, Natalia Bottasso-Arias, Megha Mohanakrishnan, John M. Snowball, Harshavardhana H. Ediga, Satish Kumar Madala, Debora I. Sinner

This study shows that Wnt signaling regulates ion channel expression, which is essential for trachealis muscle and cartilage development in mice.

American Journal of Physiology-Lung Cellular and Molecular Physiology · Oct 24, 2023Peer-reviewedDevelopmental Biology

Pan-transcriptome-based Candidate Therapeutic Discovery for Idiopathic Pulmonary Fibrosis

Yunguan Wang, Jaswanth Yella, Sudhir K. Ghandikota, Tejaswini C. Cherukuri, Harshavardhana H. Ediga, Satish Kumar Madala, Anil Goud Jegga

This study identifies 77 potential therapeutics for IPF by analyzing gene expression and drug-perturbagen connectivity, including FDA-approved drugs and clinical trial compounds.

Therapeutic Advances in Respiratory Disease · Jan 1, 2020Peer-reviewedGenomics