Author

Ming‐Qiang Zheng

Yale UniversityORCID 0000-0002-2814-8213Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:imaging· 2 Organism:non-human primate· 2 Organism:rat· 1

Frequent Co-Authors

Daniel HoldeniD· 2 shared Richard E. CarsoniD· 2 shared Zhengxin CaiiD· 2 shared Baosheng Chen· 1 shared Chao ZhengiD· 1 shared Christina Sun· 1 shared Claudia Esposito-ZaperoiD· 1 shared Clement Korsah· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Daniel HoldenORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 19, 2026

Preclinical Evaluation of Itareparib, a brain penetrant PARP1-selective radioligand, in Glioma Rat Model and Nonhuman Primate

Peng Wen Tan, Nira Hernandez Martin, Claudia Esposito-Zapero…·Zhengxin Cai

This study evaluates [18F]Itareparib as a PARP1-selective radioligand for PET imaging of gliomas, showing brain penetration and specific tumor uptake in rat models and nonhuman primates.

DOI 10.64898/2026.10.16.758050

ratnon-human primate

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NeuroscienceEuropean Journal of Nuclear Medicine and Molecular ImagingPeer-reviewedNov 10, 2021

A metabolically stable PET tracer for imaging synaptic vesicle protein 2A: Synthesis and preclinical characterization of SDM-16

Chao Zheng, Daniel Holden, Ming‐Qiang Zheng…·Zhengxin Cai

This paper develops and evaluates [18F]SDM-16, a metabolically stable SV2A PET tracer, showing high affinity and specific binding in nonhuman primate brains.

36 citations

non-human primateimaging

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