NeurosciencebioRxivPreprint
Adeno-associated virus (AAV) reduces cortical dendritic complexity in a TLR9-dependent manner
Christos Michael Suriano, Jessica L. Verpeut, Neerav Kumar…·Lisa M. Boulanger
This study shows that AAV triggers dendritic complexity loss in the cortex via TLR9, independent of capsid or transgene, and identifies TLR9 inhibitors as potential safety improvements.
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