Ofer Rog

The paper introduces PhIAT, a method using PhiC31 integrase to efficiently integrate extrachromosomal arrays into C. elegans chromosomes, enabling stable genomic modifications.

The paper introduces CheC-PLS, a proximity-labeling technique that uses Nanopore sequencing to decode chromosome organization by identifying methylated bases along long reads, demonstrating its application in budding yeast.

The paper compares T2T genomes of C. nigoni and C. briggsae, finding that self-fertilization is associated with loss of satellite DNA, particularly on the X chromosome.

The paper measures repair kinetics during C. elegans meiosis and finds similar rates for sister- and homolog-directed repair, challenging the assumption of homolog bias.

This study shows that sister chromatids are resolved early in C. elegans meiosis, and that cohesin activity is required for this resolution, which enables homolog bias in recombination.

The paper identifies the axis-central region interface in the synaptonemal complex of C. elegans and shows that liquid-like assembly occurs through wetting without active energy consumption.

The paper tests if diffusion within the synaptonemal complex can explain signal transduction along meiotic chromosomes in C. elegans.

The paper identifies Skp1 as a conserved structural component of the meiotic synaptonemal complex in nematodes, showing its role in SC assembly and fertility.

This study shows BRCA1/BRC-1 and SMC-5/6 regulate DNA repair pathways during C. elegans meiosis, limiting intersister crossover and error-prone repair.

The paper identifies the epigenetic toolkit of Pristionchus pacificus, revealing the loss of the PRC2 complex and the presence of H3K27me3 through an unknown methyltransferase.

The paper identifies a multi-protein interaction interface in the C. elegans synaptonemal complex through a suppressor screen, showing its role in stabilizing chromosome interactions.