Jiacheng Wang

Hydrostatic pressure shapes and canalizes semicircular canal morphology to ensure vestibular function

The paper shows hydrostatic pressure from the inflating otic vesicle shapes zebrafish semicircular canals, driving pillars toward a common geometry and ensuring vestibular function.

Versican controlled by Lmx1b regulates hyaluronate density and hydration for semicircular canal morphogenesis

The paper identifies Lmx1b as a regulator of hyaluronan and Versican in zebrafish inner ear semicircular canal morphogenesis, showing how Versican controls hyaluronate density and hydration through its core and chondroitin side chains.