Yusuke Mori

The paper shows Yap mechanotransduction creates a self-limiting feedback loop for zebrafish semicircular canal formation, integrating mechanical forces and transcriptional responses to ensure robust development.

The paper identifies Lmx1b as a regulator of hyaluronan and Versican in zebrafish inner ear semicircular canal morphogenesis, showing how Versican controls hyaluronate density and hydration through its core and chondroitin side chains.