Author

Malte Buchholz

Philipps University of MarburgORCID 0000-0002-2833-995XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Andrea NistiD· 1 shared Anna Mary SteitziD· 1 shared Bastian StielowiD· 1 shared Clara SimoniD· 1 shared Florian T. SchmidiD· 1 shared Hans Armin KestleriD· 1 shared Ignasi FornéiD· 1 shared Inka D. Brunke· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Andrea NistORCID

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2 papers

Recent·Most cited

SAMD1 suppresses epithelial-mesenchymal transition (EMT) pathways in pancreatic ductal adenocarcinoma

Clara Simon, Inka D. Brunke, Bastian Stielow, Ignasi Forné, Anna Mary Steitz, Merle Geller, Iris Rohner, Lisa Marie Weber, Sabrina Fischer, Lea Marie Jeude, Theresa Huber, Andrea Nist, Thorsten Stiewe, Magdalena Huber, Malte Buchholz, Robert Liefke

This study identifies SAMD1 as a repressor of EMT-related genes in PDAC, showing that its loss increases migration and that FBXO11 ubiquitinates SAMD1 to inhibit its function.

PLoS Biology · Aug 13, 2024Peer-reviewedMolecular Biology

Identification of biological mechanisms by semantic classifier systems

Ludwig M. Lausser, Florian T. Schmid, Lea Siegle, Rolf Hühne, Malte Buchholz, Hans Armin Kestler

The paper develops a semantic classifier system that uses biological knowledge to generate hypotheses about genetic configurations of phenotypes from datasets.

bioRxiv · May 31, 2018 · PreprintSystems Biology