Noncanonical CD11b on CD8+ T cells promotes cytotoxic effector function
Jone Etxaniz-Díaz de Durana, Alexandre Bosch, Endika Prieto‐Fernández, Lorena Pérez, Kexin Yu, Paloma Velasco-Beltrán, Leire Egia‐Mendikute, Iker Oyenarte, So Young Lee, Ander de Blas, Iñaki Eguren‐Santamaría, Jesús Jiménez‐Barbero, Miguel F. Sanmamed, María M. Caffarel, Ana María Aransay, , Asier Antoñana-Vildosola
This study identifies CD11b as a noncanonical marker of cytotoxic competence in CD8+ T cells, enhancing their antitumor activity in mouse and human tumors.
bioRxiv · Oct 14, 2026 · PreprintImmunology