Ana María Aransay

This study identifies CD11b as a noncanonical marker of cytotoxic competence in CD8+ T cells, enhancing their antitumor activity in mouse and human tumors.

eRREMS improves CpG coverage in methylome sequencing by combining MspI and HaeIII digestion, outperforming RRBS and WGBS in capturing regulatory CpGs.

This study identifies a proliferative-to-quiescent switch in microglial development and links it to epigenetic regulation and phagocytic function.

This paper integrates five vertebrate single-cell multi-omic atlases to reveal a conserved cellular blueprint and dual evolutionary constraints underlying early brain conservation across vertebrates.

This study characterizes the transcriptome of metastatic hormone-naive prostate cancer, identifying stroma remodelling and SOX11's role in metastasis.

The paper investigates the relationship between mitochondrial dysfunction and anti-TNF treatment response in ulcerative colitis using both murine and human samples, finding metabolic pathways and mitochondrial homeostasis are involved.

This study compares the development and evolution of sensory circuits in the pallium of birds, lizards, and mammals, revealing divergent developmental trajectories but functional similarity in sensory processing.

The paper identifies TCF19 as an androgen-responsive gene upregulated in metastatic prostate cancer, showing its role in vessel homeostasis and metastatic progression.

This study shows that Candida albicans promotes melanoma aggressiveness by activating p38-MAPK and HIF-1α pathways and inducing metabolic reprogramming.

This paper describes a synthetic CRISPR-Cas nuclease with expanded enzymatic activities, capable of targeting various nucleic acids and functioning in human cells and bacteria.

BirthSeq isolates and analyzes cells based on their birth date across vertebrate tissues, enabling temporal studies of cell fate in development.