Author

Tommaso Marchetti

École Polytechnique Fédérale de LausanneORCID 0000-0002-2884-1472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Andrea ContestabileiD· 1 shared Diana TintoriD· 1 shared Diego GhezziiD· 1 shared Jana Pachlopnik SchmidiD· 1 shared Laura CanceddaiD· 1 shared Laura E. PerliniiD· 1 shared Martina Parrini· 1 shared Naïg Aurélia Ludmilla ChenaisiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Andrea ContestabileORCID

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2 papers

Recent·Most cited

Cytokine-Induced Cell Exhaustion to Mitigate Hyperinflammation

Tommaso Marchetti, Samantha Milanesi, Diana Tintor, Tiziana Lorenzini, Severin Walser, Stefano Vavassori, Onur Boyman, Jana Pachlopnik Schmid

This study shows that targeted IL-2 treatment reduces hyperinflammation in a perforin-deficient mouse model of HLH by inducing CD8+ T cell exhaustion.

bioRxiv · Aug 12, 2024 · PreprintImmunology

Gene editing preserves visual function in a mouse model of retinal degeneration

Paola Vagni, Laura E. Perlini, Naïg Aurélia Ludmilla Chenais, Tommaso Marchetti, Martina Parrini, Andrea Contestabile, Laura Cancedda, Diego Ghezzi

This study uses CRISPR/Cas9 gene editing in a mouse model of retinal degeneration to preserve visual function, showing improved acuity and preserved light responses.

Frontiers in Neuroscience · Sep 10, 2019Peer-reviewedNeuroscience