Author

Vincent B. Luscombe

University of OxfordORCID 0000-0002-2886-4017Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Akim Abdul GuseinoviD· 1 shared Angela J. RusselliD· 1 shared Arun RajaiD· 1 shared Carl von HallersteiniD· 1 shared Cheng ZhangiD· 1 shared David R. GreavesiD· 1 shared Graeme MilliganiD· 1 shared Irina G. TikhonovaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Akim Abdul GuseinovORCID

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1 paper

Recent·Most cited

Steric control of signaling bias in the immunometabolic receptor GPR84

Pinqi Wang, Xuan Zhang, Akim Abdul Guseinov, Laura Jenkins, Carl von Hallerstein, Jonathan D. Colburn, Rowan Ives, Vincent B. Luscombe, Sara Marsango, Listiana Oktavia, Arun Raja, David R. Greaves, Philip Charles Biggin, Graeme Milligan, Cheng Zhang, , Angela J. Russell

The paper identifies ligands with varying steric profiles that exhibit different β-arrestin recruitment capacities at GPR84, revealing a mechanism for controlling signaling bias.

Nature Communications · Sep 5, 2026Peer-reviewedPharmacology & Toxicology