Gönen Memişoğlu

Prolonged Cell Cycle Arrest in Response to DNA damage in Yeast Requires the Maintenance of DNA Damage Signaling and the Spindle Assembly Checkpoint

This study shows that prolonged cell cycle arrest in yeast after DNA damage requires both DNA damage checkpoint (DDC) and spindle assembly checkpoint (SAC) proteins, with a handoff from DDC to SAC components after 15 hours.

The Mediator Kinase Module regulates cell cycle re-entry and transcriptional responses following DNA damage

The paper identifies the Mediator Kinase Module's role in DNA damage response and transcriptional regulation across species.

Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication

The paper investigates how nucleosome dynamics and eviction after a double-strand break are reversible via NHEJ repair in yeast, showing re-establishment of chromatin structure in G1-arrested cells.