NeuroscienceeLifePeer-reviewed
FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD
Yuzo Fujino, Morio Ueyama, Taro Ishiguro…·Yoshitaka Nagai
This study shows FUS suppresses RAN translation by modulating G-quadruplex structure of GGGGCC repeat RNA, reducing neurodegeneration in C9-ALS/FTD model flies.
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