Hideki Mochizuki

Tegmental atrophy in isolated REM sleep behaviour disorder: Ex vivo-informed in vivo imaging

This study identifies tegmental atrophy in iRBD using VBM and a novel brainstem atlas, linking atrophy in specific nuclei to autonomic dysfunction.

Transcriptome Analysis Identified SPP1+ Monocytes as a Key in Extracellular Matrix Formation in Thrombi

The paper identifies SPP1+ monocytes as key to extracellular matrix formation in thrombi using RNA sequencing and single-cell RNA sequencing, suggesting therapeutic targets for antithrombotic strategies.

Establishing an AI-based evaluation system that quantifies social/pathophysiological behaviors of common marmosets

This paper develops an AI system to quantify social and pathophysiological behaviors in common marmosets using 3D pose estimation and unsupervised analysis.

Quantification of escape from X chromosome inactivation with single-cell omics datasets reveals heterogeneity across cell types and tissues

The paper introduces scLinaX, a method to quantify X chromosome inactivation escape using scRNA-seq, revealing heterogeneity across cell types and tissues.

FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD

This study shows FUS suppresses RAN translation by modulating G-quadruplex structure of GGGGCC repeat RNA, reducing neurodegeneration in C9-ALS/FTD model flies.