Author

Hidehiro Mizusawa

Tokyo Medical and Dental University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Kinya IshikawaiD· 2 shared Osamu OnoderaiD· 2 shared Akihide KoyamaiD· 1 shared Akio KikuchiiD· 1 shared Akira IshiguroiD· 1 shared Akiyoshi KakitaiD· 1 shared Alessandro FillaiD· 1 shared Alexandra DürriD· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Kinya IshikawaORCID

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3 papers

Recent·Most cited

Genome-wide association study identifies a new susceptibility locus in PLA2G4C for Multiple System Atrophy.

Yasuo Nakahara, Jun Mitsui, Hidetoshi Date, Kristine Joyce L. Porto, Yasuhiro Hayashi, Atsushi Yamashita, Yoshio Kusakabe, Takashi Matsukawa, Hiroyuki Ishiura, Tsutomu Yasuda, Atsushi Iwata, Jun Goto, Yaeko Ichikawa, Yoshio Momose, Yuji Takahashi, , Shoji Tsuji

This study identifies a new susceptibility locus, PLA2G4C, for Multiple System Atrophy through a genome-wide association study and functional analysis of a risk variant.

medRxiv · May 2, 2023 · PreprintGenetic & Genomic Medicine

FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD

Yuzo Fujino, Morio Ueyama, Taro Ishiguro, Daisaku Ozawa, Hayato Ito, Toshihiko Sugiki, Asako Murata, Akira Ishiguro, Tania F. Gendron, Kohji Mori, Eiichi Tokuda, Tomoya Taminato, Takuya Konno, Akihide Koyama, Yuya Kawabe, , Yoshitaka Nagai

This study shows FUS suppresses RAN translation by modulating G-quadruplex structure of GGGGCC repeat RNA, reducing neurodegeneration in C9-ALS/FTD model flies.

eLife · Feb 13, 2023Peer-reviewedNeuroscience

Age of onset in genetic prion disease and the design of preventive clinical trials

Eric Vallabh Minikel, Sonia M. Vallabh, Margaret C. Orseth, Jean‐Philippe Brandel, Stéphane Haı̈k, Jean Laplanche, Inga Zerr, Piero Parchi, Sabina Capellari, Jiri Safar, Janna Kenny, Jamie C Fong, Leonel Tadao Takada, Claudia Ponto, Péter Hermann, , Simon Mead

This paper quantifies the challenges of designing preventive clinical trials for genetic prion disease due to high variability in age of onset, suggesting the need for biomarker-based trials.

Neurology · Jun 6, 2019Peer-reviewedNeuroscience