NeurosciencebioRxivPreprint
Ile35 residue of SOD1 plays a key role in aggregate formation and eye degeneration in a Drosophila model of ALS
DOI 10.64898/2026.09.13.751333
Author
Kindai UniversityORCID 0000-0002-1773-8998Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Hayato Ito, Kodai Machida, Yuzo Fujino…·Hideki Taguchi
The paper identifies eIF1A and eIF5B as repressors of C9orf72-mediated RAN translation by showing their omission enhances RAN translation in all reading frames.
Yuzo Fujino, Morio Ueyama, Taro Ishiguro…·Yoshitaka Nagai
This study shows FUS suppresses RAN translation by modulating G-quadruplex structure of GGGGCC repeat RNA, reducing neurodegeneration in C9-ALS/FTD model flies.